Deer Truffle

Common Name: Deer Truffle, Deer balls, Hart’s balls, Warty deer truffle, Fungus cervinus (cervus is Latin for deer), Lycoperdon nuts (Lycoperdon is a genus of puffball fungi) – Truffle is a French variant of the Latin word tuber meaning lump or knob. Both truffles and tubers (like potatoes) are generally globular in shape. The association with deer is attributed to finding them in locations frequented by stags during mating season. This gave rise to the belief that truffles are aphrodisiacs.

Scientific Name: Elaphomyces granulata – The generic name is a literal translation of Greek, deer (elaphos) fungus (mykes). The Latin granulum is used directly in English as granule, referring here to the protuberances on an otherwise smooth surface. A loose translation of the scientific name would be “warty deer fungus,” one of the common names.

Potpourri: The deer truffle genus Elaphomyces is one of the most important mycorrhizal genera in temperate and subarctic forests, establishing and maintaining the ecosystem balance between plants and fungi. They are also an important source of food for small mammals like mice and voles on every continent except Antarctica. Deer truffles are equally favored by their namesake, notably the red, roe, and fallow deer species of Europe. Of the 49 species of deer truffle so far recognized worldwide, 20 are European. E. granulatus is one of the most important North American species. A related species, E. muricatus, has been used in Mexico, both as “a stimulant, for remaining young and treating serious wounds” and “in shamanic practices in association with psychoactive Psilocybe species.” [1] Limited research in the 21st century has revealed that E. granulatus has enzymes that are known to reduce inflammation in addition to a variety of anti-oxidants with potential medicinal applications for humans.

Deer truffes are among the most common of underground fungi globally, and equally one of the least documented. The lack of scientific research on deer truffles is due partly to their sub rosa, subterranean obscurity and ignorance about their ecological importance. Even when uncovered, they look like lumpy balls of dirt. However, unlike the more famous black and white truffles of Europe, they are neither redolent with beguiling aromas nor palatable. Taste testers report that the main body is like “thick cream that tastes like nothing,” a rind that is “rubbery but can be chewed quickly,” and “a taste that goes in the direction of earthy forest floor.” They are, nonetheless, relished by rodents. [2]

Truffle is defined as “any of an order (Tuberales) of fleshy, edible, potato-shaped ascomycetous fungi that grow underground.” However, truffle is broadly applied to any hypogenous (below ground) fungus that is shaped like a tuber, which is the thickened part of an underground plant stem like those of the yam, cassava, and potato. According to historical etymology, any roundish shaped globule dug out of the ground was a tuber and/or truffle. [3] The distinction between plant and fungi kingdoms was not established until the 20^th century so it would have made no difference whether the earthen globule was a plant tuber or a fungal truffle. The lumpiness meaning is inherent in chocolate truffle, a confection shaped like a truffle having no fungal ingredients. The terms edible and ascomycetous in the definition require some elucidation.

Edible does not necessarily mean by humans, but merely that it is or can be eaten for nutrition by an animal. Being edible is also a matter of importance, as fungal truffles reproduce by spores that must be transported for propagation. Above ground or epigenous fungi/mushrooms accomplish this with airborne wind dispersion, a mechanism not available to truffles buried several centimeters deep. Truffles must usually be consumed by an animal to transport the spores to new fertile ground and must thus be at least palatable. The need to attract animals is key to the inimitable smell and taste of certain species of truffles. It is probable that some truffles are unearthed and broken open without being eaten to release spores, so consumption is not absolutely mandatory although certainly the norm. Insects and worms that tend to feed on fungi may also play a role. Edible is a broad term in this context.

The term ascomycetous is a bit more complicated. The vast majority of fungi typically called mushrooms are in the subkingdom Dikarya which means “two nuclei” in Greek. Dikaryotic cells replicate with cell division of one nucleus from one “parent” and one from the other as they grow so that each new cell has two nuclei until the creation of reproductive spores through meiosis to pass the combined DNA to future generations. The way in which spores are produced divides Dikarya into two phyla, Basidiomycota and Ascomycota. Basidiomycetes produce four spores at the end of a club-shaped structure called a basidium. Most of the fungi that look like a mushroom with a cap or pileus at the top of a stem or stipe in addition to the various bracket fungi, puffballs, and stinkhorns fall into this category. Ascomycetes produce eight spores inside a sac-like structure called an ascus, Greek for wineskin or bladder. The asci are typically arrayed on a concave surface giving rise to the more common name “cup fungi” for ascomycetes. Most fungi, including yeasts, rusts, smuts, lichens, and, notably, truffles are ascomycetes. [4] False truffles are basidiomycetes that look like truffles―ball-shaped structures that grow below ground.

Both truffles and false truffles followed different ancestral trajectories to become nearly identical in size, shape, and disposition due to similar environmental factors, a process called convergent evolution. Richard Dawkins offers that this is because “however many ways there may be of being alive, it is certain that there are vastly more ways of being dead.” Organisms tend to come up with similar ways to survive in the unforgiving environments of nature. Life above ground can be dangerous due to predatory and environmental challenges making it advantageous to seek refuge in the soil. Many animals also do this. It is hypothesized that truffles evolved from cup fungi and false truffles evolved from mushrooms like agarics and boletes as a matter of random mutation resulting in improved survival. However, it could equally be the other way around, i.e. fungi may have originally been underground ”truffles” and evolved mushroom stems and gills for spore wind dispersion. DNA sequencing of the world-renowned Périgord black truffle corroborated the estimate that Pezizomycetes, the largest group of Ascomycota that includes truffles, separated from other fungal lineages 450 million years ago, just as the first plants advanced onto land from the sea. [5]

Deer truffles from Germany. Note root-like attachment to the mycelium.

Most fungi start as a root-like structure called a hypha emanating from one spore joining up with another hypha from another spore to form a mycelium, the tangled mass of hyphae that defines the fungus. Since no species can survive without reproducing at some point, the mycelium must somehow send spores somewhere to start anew. Just as plants have devised ingenious ways to spread seeds, so have fungi to spread spores. Mushrooms start as underground bodies called primordia that are formed by the mycelium. They erupt upward on a stem into open air when the time is right to expose the spore bearing gill or pore surface to transporting winds. In the case of truffles and false truffles, the spores are contained in the tuber-like body that is attached to and grows from the mycelium but remains underground. The evolutionary pathway for the truffles and false truffles was to attract animals with enticing smells, not all that different from plants producing flowers with complex chemical scents to attract pollinators. Note that it is important for truffle smell signaling to start only when the spores are fully mature and ready to transport. Animals drawn by the smell to eat them transport truffle spores unwittingly wherever and whenever they “go.” [6]

Animals attracted to truffles and false truffles are globally diverse, inclusive of deer, bears, and rabbits in the Northern Hemisphere and armadillos, baboons, and wallabies in the Southern Hemisphere. [7] Underground fungi offer a food source that is relatively independent of surface conditions making them especially important to cohabitating animals. While most if not all forest dwelling mammals consume truffles on occasion, it is the burrowing squirrels and voles that are best equipped to use them as a major food source. With a keen sense of smell and claws to dig up buried acorns, there can be no doubt that squirrels are truffle aficionados. One well studied example is the California red-backed vole of the Pacific Northwest which subsists almost entirely on truffles. A study in the Oregon Coast Range involving vole capture and evisceration found that truffles made up 85 percent of consumed food, the balance was mostly lichens, also predominantly fungal. The northern flying squirrel, with a range from Alaska to North Carolina, is a nationwide spreader of truffle spores. [8] The extent of the role that truffles play in forest ecology as both providers of key soil nutrients like phosphorous and nitrogen to trees and as food for foragers is not well studied and therefore mostly unknown. This relationship is called mycorrhizal (meaning fungus root in Greek) and was first discovered by a biologist named Albert Frank in 1885 while employed by the King of Prussia to attempt to cultivate truffles. [9] Since there is no above ground evidence and animals need to be literally caught in the act, data are mostly anecdotal. However, one can gather some insight of the range, diversity, and importance of truffles from the aptly named “desert truffles.”

A desert is a dry, barren place incapable of supporting almost any plant or animal life. And yet, truffles thrive across North Africa and the Middle East all the way to China. Eking out a tenuous existence with shrubby plants with which they are mycorrhizal, they are surprisingly ubiquitous. They are sold in many local markets and consumed as an important food source over a vast region, noted for having a taste characterized as “delicate, not pungent.” They are reportedly relatively easy to find as they grow close to the surface and make the ground harder, a property that can be discerned with experience by rubbing a bare toe over the area. [10] As Mesopotamia was the cradle of western civilization, the long history of truffles as both food and medicine there is telling. Truffles have historically been a substitute for meat throughout the Arabian peninsula. Truffles (kama’ah in Arabic) appear in the Koran as preventive medicine, used as promoters of longevity and good health much as many other fungi are in Asia. This a measure of their reputed anti-oxidant, anti-inflammatory, and immune modulating activity. 11] The cultural importance and extensive range of desert truffles across a broad swath of Eurasia is a strong indicator that they are key components of the plant-fungi global ecological partnership. While truffles are surely common and keystone in many regions, almost all of what is known and studied about the nature and nurture of truffles derives almost in entirety from detailed study of a few species that are among those granted the rubric “true truffles.”

True truffles are the epitome of European gastronomy. The black truffle of the Périgord region in southern France (Tuber melanosporum) is surpassed only by the white truffle of the Piedmont region of northern Italy (Tuber magnatum) in desirability and exorbitant cost. The reason for the difference is supply and demand, the universal economic law. White truffles are rarer because, unlike their cultivated French cousins, they grow only under naturally appropriate conditions and require specialized skills to locate. Consequently, in local Italian trattoria, one can purchase risotto with black truffles for about 20 euros, but risotto with white truffles will run over five times as much. [12] The reason for truffle demand is the redolence they impart to food, beguiling gourmands in their search for epicurean nirvana. It is telling that truffles were originally hunted with domesticated female pigs attracted by their aroma which includes the steroid alpha-androstenol, also found in the saliva (and breath) of rutting boars. The same chemical is found in the underarm emanations of men and in the urine of women, and, while the sexual role of the steroid in human sexuality has not been proven, it has been demonstrated. Men rating photographs of (clothed) women for sexual attractiveness gave higher marks when smelling alpha-androstenol. [13] In that smell is intertwined with taste according to the neural-networked brain, the irresistible allure of truffles to humans probably has deeper meaning and possibly including subliminal sexual arousal. It is no wonder that they are considered to be aphrodisiacs. Perhaps at least mentally they are.

It is almost certain that boars that have roamed wild across Europe for millennia were the coevolutionary partners of white and black truffles, spreading their spores far and wide. It is probable that humans first became aware of truffles in association with hunting wild boars. Thus began the long partnership between domesticated pigs and people in the pursuit of pleasure. Dogs have mostly replaced pigs as the truffle hunter’s sensory companion. Heavy, sedentary pigs required carting to truffle forest habitats and had to be forcibly prevented from eating their quarry; many a truffle hunter lost a finger to an overzealous pig. Dogs are not sexually attracted to truffles and must therefore receive olfactory training, much like drug-sniffing dogs of the DEA. This takes a great deal of time and effort, which must of necessity include the use of valuable, short-lived truffles. Trained truffle dogs are dear, commanding prices of over 15,000 euros but rarely sold. They can transit and search woodlands with ease and are not overwhelmed by lust for consumption. In fact, most truffle dogs don’t even like them, though apparently some do. Dogs have different taste preferences, as do their best friends. But not pigs, apparently. [14] The wild boar fungus story has a recently discovered twist. Of 48 boars killed in hunts in Bavaria, Germany, 88 percent had radioactive cesium levels (from Chernobyl) exceeding safety standards. It is considered likely that eating fungi that tend to bioaccumulate heavy metals were the source, especially truffles. [15]

References:

1. Paz, A. et al . “The genus Elaphomyces (Ascomycota, Eurotiales): a ribosomal DNA-based phylogeny and revised systematics of European ‘deer truffles'”. Persoonia. 30 June 2017. Volume 38 Number 1 pp 197–239.

2. “Deer Truffles – biology, ecology, distribution and occurrence of Elaphomyces or False truffle” https://www.umweltanalysen.com/en/elaphomyces-deer-truffles/

3. Neufeldt. V. ed Webster’s New World Dictionary of American English, Third College Edition, Simon and Schuster, New York, 1988, p 1435, 1438.

4. Lincoff, G. National Audubon Society Field Guide to North American Mushrooms, Alfred A. Knopf, New York, 1981, pp 323, 377.

5. Martin, F. et al “Périgord black truffle genome uncovers evolutionary origins and mechanisms of symbiosis” Nature, 28 March 2010, Volume 464 pp 1033-1038. https://www.nature.com/articles/nature08867

6. Arora, D. Mushrooms Demystified, Second Edition, Ten Speed Press, Berkeley, California, 1986 pp 739-741, 841-865.

7. Trappe J. and Claridge A.” The Hidden Life of Truffles” Scientific American April 2010.

8. Stephenson, S. The Kingdom Fungi, Timber Press, Portland, Oregon, 2010 pp 200-205.

9. Frank, A.B. “Über die auf Wurzelsymbiose beruhende Ernährung gewisser Bäume durch unterirdische Pilze” [On the nourishing, via root symbiosis, of certain trees by underground fungi]. Berichte der Deutschen Botanischen Gesellschaft. 1885 Volume 3: pp 128–145.

10. Schaechter. E. In the Company of Mushrooms, Harvard University Press, Cambridge, Massachusetts, 1997, pp 161-167.

11. Khalifa, S. et al “Truffles: From Islamic culture to chemistry, pharmacology, and food trends in recent times” Trends in Science and Food Technology, Volume 91, September 2019, pp 193-218. https://www.sciencedirect.com/science/article/abs/pii/S0924224418303406

12. Goldhor, S. “Hunting the White Truffle” Fungi. Volume 8 Number 3, Fall 2015, pp 18-23.

13. Kendrick, B. The Fifth Kingdom, Third Edition, Focus Publishing, Newburyport, Massachusetts, 2000 pp 281-283.

14. Campbell, D. “Sketches from the Italian Truffle Hunt.” Fungi, Volume 11 Number 1, Spring 2018, pp 20-25.

15. Rains, M. “Germany’s radioactive boars are a bristly reminder of nuclear fallout” Science, 30 August 2023.

Raspberry

Black raspberries turn from red to black when fully ripe

Common Name: Raspberry, Black raspberry (photo above. Note that black raspberries are initially red), Blackcap, Thimbleberry, Framboisier noir (Quebec) – The etymology of raspberry is uncertain. One hypothesis is that it is simply a combination of rasp in the sense of being rough or harsh from French rasper, to scrape together. An alternative origin is from raspis, a sweet red wine popular in Europe in the Middle Ages. Berry is from beri, a Germanic word for grape. The red raspberry is also known as European red raspberry.

Scientific Name: Rubus occidentalis (black raspberry) and Rubus idaeus (red raspberry) – Rubus is Latin for bramble-bush and, by extension, blackberry. The species occidentalis is from the Latin occidens meaning to go down or set, generally used to refer to the western hemisphere. The Black raspberry is indigenous to eastern North America where it was first classified. The species idaeus refers to Mount Ida in Asia Minor, where red raspberries originated.

Potpourri: The ubiquitous raspberry was indisputably one of the first plants to be recognized as a source of food for many animals, especially the naked apes that eventually evolved to Homo sapiens about 60,000 years ago. The prominently colorful berries, raspberry red in Eurasia where they originated, stood out from the verdant foliage, a distinction unseen by other mammals lacking the red vision of primates. Raspberries were almost certainly spread globally by migrating birds where new species arose as a result of evolutionary diverse habitats. In its current bramble form, raspberries resist consumption of its growing plant parts with conspicuous thorny outgrowths characteristic of its Rose Family taxonomy. Growing in dense thickets from root extensions called rhizomes, brambles like raspberry produce copious quantities of enticing berries to perpetuate its dominance in open, sunny areas. Black raspberries form impenetrable hedges along many trails, offering a succulent snack and an occasional prick to passing hikers.

Raspberries are aggregate fruits with prickles

Raspberries are not berries and they do not have thorns. The fruit is an aggregate, and the sharp-pointed protuberance is a prickle. The use of berry for any small, roundish fruit is as fraught in common parlance as the distinction between fruits and vegetables. A fruit is “a ripened ovary and its contents together with any adjacent parts that may be fused to it.” Fruits are the seed carriers of propagation. Grains like barley, vegetables like peas, and nuts like acorns are fruits. A fruit “in which the entire ovary ripens into a fleshy, often juicy and edible” is the botanist’s berry, inclusive of tomatoes, eggplant, red peppers, and watermelons. A drupe is different, having a layered ovary that gives rise to a central stone or pit that encloses the seed, like plums and peaches. Raspberries arise from flowers with multiple pistils (central organ of a flower), each producing a small drupe, sometimes called a drupelet. The multiple small fruits cling together, separating as a single unit that is called an aggregate. Rasp-aggregate would be a more correct name, but hardly useful. Spines, thorns, and prickles are all sharp-pointed outgrowths from a plant surface that evolved to repel herbivores. Spines like those on barberries originated from leaves. Thorns like those on Osage orange arose from branches. Prickles like those on raspberries are the real stickers, emerging directly from stem tissues. [1]

Raspberries are classified as members of Rosaceae, the family of roses in the genus Rubus, known colloquially as brambles. With about 3,000 species, the rose family is not that large compared to the 20,000 species of the orchid family and 19,000 species of the composite family, inclusive of asters, daisies, and sunflowers. [2] However, the rose family is arguably the most renowned of all plant families from the human perspective. Its prominent floral and fruit products that proliferate the temperate zones of primary habitation are without equal in the kingdom Plantae. In addition to the many cultivars of roses that dominate the floral trade, they are the sine qua non for spectacles like the annual Pasadena parade and namesake bowl game and Kentucky’s running of the roses in the first of the three horseracing crowns. English wars have been named for them. The red rose Lancasters and white rose Yorks have nothing to do with the Lannisters and Starks even though they were both involved in throne games of a sort. However, the fruits of the rose family that dominate at the supermarket are its most enduring legacy. Life would be lessened absent apples, pears, cherries, plums, and the various bramble berries. The success of the rose family is a result of the evolution of a number of traits that promote reproduction and dispersion. Having a diversity of fruits with the color, shape, and taste that appeal to birds and mammals results in spreading seeds far and wide in a dollop of fertilizer. More important, however, is asexual reproduction called apomixis by which rose plants can spread without pollinators. This is especially true of the brambles like raspberry that extend by horizonal, leafless stem structures called rhizomes. [3]

Rose family fruits in general and raspberries in particular have spread far and wide, part of Darwin’s “endless forms most beautiful and most wonderful” due to hybridization that results from a combination of seed dispersion and asexual apomixis. Apples abound in variety and raspberries are not far behind. There were already 41 varieties of raspberry in the United States in 1866. [4] Both apples and raspberries tend toward polyploidy, having multiples of the basic number of chromosomes, which can result in the reestablishment of sexuality to create new hybrids. This is further complicated with raspberries, that can have one of three different basic chromosome numbers (7, 8, or 9) to start with. This means that from their inception in Asia Minor, raspberries have spread across the globe in many hybrid forms, drawing the attention of the hominids doing the same thing. That they were well known by the time of the Roman Empire is well established. Pliny the Elder (aka Gaius Plinius Secundus), the noted Roman military leader and naturalist author, wrote in his magnum opus Naturalis Historia that the raspberry was “known to the Greeks as the Idæan bramble, from the place where it grows.” Mount Ida is in Northwestern Turkey near the site of Troy, providing the species name idaeus of red raspberry. It was even then regarded as a medicinal plant, for Pliny notes that: “Its flower, mixed with honey, is employed as an ointment for sore eyes and erysipelas, and an infusion of it in water is used for diseases of the stomach.” [5] As raspberry seeds have been found at Roman forts on the British Isles, it is considered likely that the Romans spread the raspberry from its Asian origins throughout their vast empire into Europe and Africa. [6]

Raspberries have served as a wellspring for both nutritious food and medicinal remedy for the millennial span of western civilization. They found their way into the various herbal collections that appeared in Europe in the late 16^th century. John Gerard, calling it the Raspis, Hinde-berry, or Framboise (French), notes that “the floures (sic), the leaves, and the unripe fruit, being chewed, stay all manner of bleedings. They heal the eies (sic) that hang out.” The ripe fruit is described as sweet, and “not unpleasant to be eaten,” [7] As the modern era erupted from the rediscovery of Greco-Roman writings in the Renaissance, the expansion of raspberries as one of the first fruits followed. By the 17^th century, white and red cultivar raspberries were recognized in Great Britain that differed only in the color and taste of the fruit, the “white raspis a little more pleasant than the red.” Red wines were available at the “vintners made from the berries of Raspis that grow in colder countries.” The medicinal uses had also expanded, extending to the use of leaves “in gargles and other decoctions that are cooling and drying, but not fully to that effect” whatever that means. A syrup made from the berries “is effectual to cool a hot stomach, helping to refresh and quicken up those that are overcome with faintness.” And of course the berries were eaten “to please the taste of the sick as well as the sound.” [8] As the consumer era took off in the middle of the last century, the raspberry became a mass market food and one of the myriad herbal remedies to assuage modern melancholia.

Raspberries are nutritious, contributing to a healthy diet. They are one of the highest sources of dietary fiber (6.5 grams fiber per 100 grams wright) relative to the energy provided (100 kilocalories per 12.5 grams). In addition, they are high in vitamins C and K and in the minerals calcium, magnesium, potassium, and iron. Raspberries also contain a unique set of phytochemicals, secondary substances not involved in plant metabolism, that are likely the basis for the many historic folk medicinal uses. Anthocyanins, which are what make berries (and fall leaves) red, are noted for their antioxidant and anti-inflammatory activity, deactivating the free radicals (ionic forms) that tend to disrupt cellular activity. In vivo animal studies have found that consuming raspberries resulted in “reduced blood pressure, improved lipid profiles, decreased atherosclerotic development, improved vascular function, stabilization of uncontrolled diabetic symptoms (e.g., glycemia), and improved functional recovery in brain injury models”. [9] It may be concluded that the use of raspberries in the treatment of a variety of ailments has at least some rational basis due to actual chemical interactions operating above and beyond the placebo effect.

Native American herbal remedies provide one of the best examples of genuine folk medicine unadulterated by marketing hucksterism. The Iroquois Confederacy of the northeast had many uses for raspberry leaves and roots, including treating bloody diarrhea, as an emetic, to remove bile, to treat children with whooping cough, and, perhaps with some hyperbole, as a “decoction taken by a hunter and his wife to prevent her from fooling around.” Raspberries were also important as food, especially in winter when dried fruits were combined with hominy. Further south, Cherokee also used raspberry plants for digestive problems and as food but in the form of pies and jellies suitable for the milder climate. On the more practical side, the prickly stems were used for scratching itchy hard to reach places. In addition, it was used for coughs, boils, and, most significantly to current usage, to treat postpartum pain. [10] Current usage as an herbal remedy follows those of Native American usage, with an emphasis on pregnancy issues.

The most prevalent use of raspberry over the last century has been during the last trimester of pregnancy to “relax the uterine muscles and facilitate birth.” [11] However, in Germany this is proscribed “because of lack of scientific support of claimed activities as a uterine tonic.” [12] The widespread use of raspberry leaves in herbal preparations for pregnancies has resulted in some serious scientific assessment. Approximately 50 percent of all pregnant women use some form of herbal treatments during pregnancy and the use of raspberry extracts as tea, tablets, or tincture ranges from 7 to 56 percent depending on the country. The claim made by the herbal industry is a “positive effect on childbirth through the induction of uterine contractions, acceleration of the cervical ripening, and shortening of childbirth.” No studies clearly demonstrate that products derived from raspberries have a clear effect on the biochemical pathways of pregnancy. A recent review concludes that “the consumption of raspberry extracts could translate into decreased dynamics, or even the inhibition of the cervical ripening process, which could undoubtedly translate into a more tumultuous and traumatic childbirth course.” It is increasingly clear in the medical community that the best way to stay healthy is to eat a balanced diet, exercise regularly, and avoid stress. Hiking along trails in the quiet of the forest and eating raspberries is a good place to start.

References:

1. Wilson, C. and Looms, W. Botany, 4^th Edition, Holt, Rinehart and Winston, New York, 1967, pp 30-31, 285-304.

2. Niering, W. and Olmstead, N. National Audubon Society Field Guide to North American Wildflowers. Alfred A. Knopf, New York, 1998, p.354, 646, 746.

3. Cowan, R. “Rosales” Encyclopedia Britannica Macropedia, William and Helen Benton, Publishers, Chicago, 1972 Volume 15, pp 1150-1154.

4. Stuart, M. ed The Encyclopedia of Herbs and Herbalism, MacDonald and Company Publishers, London, 1987, p 255.

5. Pliny the Elder, The Natural History – John Bostock, M.D., F.R.S. H.T. Riley, Esq., B.A. London. Taylor and Francis, Red Lion Court, Fleet Street. 1855. Book 16 Chapter 71 – https://www.perseus.tufts.edu/hopper/text?doc=Perseus:text:1999.02.0137:book=16:chapter=71&highlight=raspberry

6. Burton-Freeman, B. et al “Red Raspberries and Their Bioactive Polyphenols: Cardiometabolic and Neuronal Health Links” Advanced Nutrition, Volume 7, Number 1 January 2016 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4717884/

7. Gerard, J. Herball – Or, Generall Historie of Plantes, John Norton, London, 1597. Pp 260-261

8. Parkinson, J. Paradisi in Sole, Paradisus Terrestris 1629. Reprinted by Methuen &Company, London, 1904, p 557 -558 https://www.gutenberg.org/files/69425/69425-h/69425-h.htm#Page_557

9. Burton-Freeman et al, op. cit.

10. Native American Ethnobotany Data Base. http://naeb.brit.org/

11, Polunin, M. and Robbins, C. The Natural Pharmacy, Collier Books, New York, 1992, p 122.

12. Foster, S. and Duke, J. Medicinal Plants and Herbs, Petterson Field Guide Series, Houghton Mifflin Company, New York, 2000, pp 264-265

13. Socha, M. et al “Raspberry Leaves and Extracts-Molecular Mechanism of Action and Its Effectiveness on Human Cervical Ripening and the Induction of Labor” Nutrients, Volume 15 Number 14, 19 July 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10383074/